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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FREM3
All Species:
8.48
Human Site:
T578
Identified Species:
26.67
UniProt:
P0C091
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P0C091
NP_001161707
2135
237764
T578
D
I
D
S
E
D
S
T
I
H
F
V
L
E
N
Chimpanzee
Pan troglodytes
XP_517461
2289
255014
T728
D
I
D
S
E
D
S
T
I
H
F
V
L
E
N
Rhesus Macaque
Macaca mulatta
XP_001092507
2276
253244
T715
D
I
D
S
E
D
S
T
I
R
F
V
L
E
K
Dog
Lupus familis
XP_543127
3169
350410
A583
I
L
P
L
A
L
S
A
A
D
I
D
S
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5H8B9
2123
234980
A570
D
I
D
S
E
D
S
A
I
L
F
V
L
E
D
Rat
Rattus norvegicus
Q00657
2326
251891
E589
Y
D
P
D
S
A
C
E
G
L
T
I
Q
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417087
3168
351300
I577
D
I
D
S
Q
D
A
I
L
L
F
T
V
E
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796581
2335
258813
R646
D
A
E
S
T
E
E
R
L
R
Y
T
I
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.2
88.7
39.3
N.A.
68
20
N.A.
N.A.
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
92.6
90.9
49.8
N.A.
80.1
35.7
N.A.
N.A.
50.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.2
P-Site Identity:
100
100
86.6
13.3
N.A.
80
0
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
86.6
26.6
N.A.
86.6
6.6
N.A.
N.A.
80
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
13
13
13
25
13
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% C
% Asp:
75
13
63
13
0
63
0
0
0
13
0
13
0
0
25
% D
% Glu:
0
0
13
0
50
13
13
13
0
0
0
0
0
75
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
63
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
13
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% H
% Ile:
13
63
0
0
0
0
0
13
50
0
13
13
13
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% K
% Leu:
0
13
0
13
0
13
0
0
25
38
0
0
50
13
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
25
% N
% Pro:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
0
0
0
13
0
0
% Q
% Arg:
0
0
0
0
0
0
0
13
0
25
0
0
0
0
0
% R
% Ser:
0
0
0
75
13
0
63
0
0
0
0
0
13
0
13
% S
% Thr:
0
0
0
0
13
0
0
38
0
0
13
25
0
13
13
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
50
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _